Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens is a deciduous shrub or small tree, commonly growing about 3 – 6 metres tall, with a broad and rather flat or sometimes narrow . PDF | Extracts from the bark of Amphipterygium adstringens, known as Cuachalalate, is in Mexico commonly used to treat several gastrointestinal disorders.

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One of these mechanisms could be related to the well-known antioxidant properties ascribed to the majority of the plant extracts, due to their content in polyphenolic compounds, as it happens with the present extract that contains flavonoids, which has been reported to exert antioxidant properties [ 3839 ].

Because of its ever-growing popularity and since the most sought after part of the plant is its bark, the cuachalalate was as of considered an endangered species. For this reason, the development of new therapies that combine efficacy, convenient dosing, and fewer side effects is an important goal in human UC therapy.

The formaldehyde produced is measured colorimetrically with 4-aminohydrazinomercapto-1,2,4-triazole Purpald as the chromogen. adstrlngens

Amphipterygium adstringens – Wikipedia

Use of complementary and alternative medicine by patients with inflammatory bowel disease. The male flower is actinomorphic.

Mice were sacrificed using CO 2 chamber, and all efforts were made to minimize pain. Antioxidant, antimicrobial and cytotoxic activities of selected medicinal plants from Yemen. Introduction Ulcerative colitis UC is a major type of inflammatory bowel disease characterized by chronic, relapsing intestinal inflammation with extensive damage of apmhipterygium mucosa.

Characterisation of complementary and alternative medicine use and its impact on medication adherence in inflammatory bowel disease. De La Rosa, qmphipterygium G. Fatty acids and inflammation: The relative amounts of the individual components were based on the peak areas. The results suggested the protective potential of AaEE in DSS-induced amphipteryvium and this might be attributed to its phytochemicals compounds that have been found to induce a wide adstringenss of activities such as reduction in oxidative stress, suppression of inflammation, modulating numerous signal transduction pathways, and induction of apoptosis.


This result comes in concordance with many previous studies that reported that GPx plays a much greater role in the removal of H 2 O 2 than CAT [ 29 — 31 ]. Strains were cultured following their specific requirements. Louis, MO, USA was used as positive control for bactericidal activity due to its antibacterial spectrum against Gram-positive and Gram-negative bacteria and actual application on oral hygiene; Fluconazole Pfizeran oral azole, was selected as positive control adstrongens Candida because it is frequently used in patients who suffer oropharyngeal and esophageal candidiasis.

Evidence-Based Complementary and Alternative Medicine

Plant Material The A. It has been proposed that an imbalance between prooxidant and antioxidant mechanisms may play an important role in the development of intestinal inflammation and mucosal tissue injury in colitis [ 27 ]. Gastroprotection and effect of the simultaneous administration of Cuachalalate Amphipterygium adstringens on the pharmacokinetics and anti-inflammatory activity of diclofenac in rats.

The experiment was performed by duplicate in three independent tests. Introduction Natural molecules and products reemerge as promising sources of complex multitarget mixtures that are used as alternative therapeutic agents for various conditions, including infections and chronic diseases [ 12 ], such as oral diseases [ 3 — 5 ] or digestive cancers [ 6 ].

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However, failures in immune defense or plaque control result in development of gingival inflammation [ 25 — 27 ]. The most sensitive strain was S. The bark has traditionally been used by healers to treat gastritis, gastric ulcers [ 9 ], gastrointestinal cancer [ 1011 ], colic, fever [ 1213 ], and also tooth pain [ 14 ]. Trees and Shrubs of Mexico pt.

In Vitro Antimicrobial and Antiproliferative Activity of Amphipterygium adstringens

The AaEE were orally administered for 10 days. The antioxidant activity was determined according to the method by Okusa et al.

Our results, along with previous reports of A. Antimicrobial activity of northwestern mexican plants against Helicobacter pylori. These results are consistent with previous work demonstrating higher sensitivity of S. CAT and GPx then transform the generated H 2 O 2 into H 2 O, thus preventing the harmful effects of oxidative radicals and the initiation processes xmphipterygium lipid peroxidation.


This page was last edited on 18 Julyat View at Google Scholar A. The standard treatments for colitis are generally immunosuppressant and anti- inflammatory drugs, which have many undesirable side effects.

However, further research should be made to test whether secondary metabolites amphippterygium A. Additionally our results provide novel evidence that A. Probability values of were considered to be significant. Journal of Nutritional Biochemistry. View at Google Scholar Adstrimgens. Epigallocatechingallate EGCGa catechin of the green tea plant Camellia sinensisshows strong expanding beneficial effects in studies of diabetes, Parkinson’s disease, Alzheimer’s disease, stroke, inflammation, obesity, and cancer [ 42 ].

In regard of activity shown against S. Cytokine blockade in inflammatory bowel diseases.

It is presented by a variety of clinical manifestations, including attacks of abdominal cramps, pain, bloody diarrhea, bleed per rectum, weight loss, fever, and easy fatigability, which may begin gradually or start totally all at once [ 12 ].

On the other hand, inflammatory responses play a critical role in the pathogenesis of UC. The untreated group received tap water without DSS. At least 3 sections from each colon were analyzed to produce each score value.

Methanolic extract of A. Amphipterygium adstringens Diederich Franz Leonhard von Schlechtendal. To receive news and publication updates for Evidence-Based Complementary and Alternative Medicine, enter your email address in the box below.

In this model, in vitro cytotoxicity determination of the CE of A. Recent studies have shown that the active component responsible for the plant properties is the anacardic acid [ 19 ] which exerts antioxidant, anti-inflammatory [ 20 ], antitumoral [ 21 ], antiulcer and antimicrobial activities [ 919 ].

The pharmacological activity of medicinal plants appeared to correlate with the presence of active compounds having antioxidant and anti-inflammatory activities.